Comptes Rendus Biologies is a peer-reviewed electronic journal whose primary objective is to publish review articles and opinion/perspective pieces aimed at a broad audience of scientists, providing an overview of important scientific issues. It is one of seven journals published by the Académie des sciences, heir to the Comptes rendus hebdomadaires des séances de l'Académie des Sciences [Weekling proceedings of the Académie des Sciences' meetings] founded in 1835 by Arago.

The journal covers all fields of life sciences. Articles can be written in English or French and there are no restrictions on length or format (figures, associated data, etc.).

Comptes Rendus Biologies only publishes articles that have been solicited by the journal's editorial board. Unsolicited submissions are not considered.

Most authors are invited to contribute after receiving an award from the Académie des sciences or as experts in a field that the editorial board wishes to highlight.

Comptes Rendus Biologies is published since 2020 with the centre Mersenne pour l'édition scientifique ouverte (Mersenne Center for open scientific publishing), according to a virtuous Diamond Open Access policy, free for authors (no publication fees) as well as for readers (immediate and perennial open access). It has been co-published with the Centre national de la recherche scientifique (CNRS) since January 1, 2026.

Editor-in-Chief: Antoine Triller.