[Optimisation de la forme d'un implant intraoculaire accommodatif]
. L'opération de la cataracte consiste à remplacer le cristallin naturel devenu opaque par une lentille intraoculaire de même puissance refractive moyenne. Après une telle intervention la vision du patient est nette à une distance fixe et il doit porter des lunettes dans de nombreuses circonstances. Nous proposons un nouvel implant qui permet de préserver au moins en partie sa capacité accommodative. Sa conception repose sur la compréhension des mécanismes de l'accommodation, la modélisation et la simulation numérique du comportement de l'implant in vivo. Une version de cet implant est actuellement fabriquée et commercialisée par la société HumanOptics sous le nom de « 1CU ». Dans une seconde phase, nous décrivons comment les techniques récentes d'optimisation de forme permettent d'améliorer le design initial.
Cataract surgery consists in replacing the clouded or opacified crystalline lens by an Intra-Ocular Lens (IOL) having the same mean dioptrical power. Clear vision is then achieved at a given distance and glasses are needed in many situations. A new kind of IOL, potentially accommodative, is proposed. Its design is based on the deep understanding of the accommodation mechanism and on the mathematical modeling and the numerical simulation of the IOL's comportment in vivo. A preliminary version of this IOL is now commercialized by the company HumanOptics under the name ‘1CU’. In a second phase, shape optimization techniques equipped with strong mechanical and physiological constraints, are used to enhance the IOL performance and build a new design.
Accepté le :
Publié le :
Mot clés : Biomécanique, Mécanique des solides numérique, Optimisation de formes
@article{CRMECA_2005__333_3_243_0,
author = {Fran\c{c}ois Jouve and Khalil Hanna},
title = {Shape optimization of an accommodative intra-ocular lens},
journal = {Comptes Rendus. M\'ecanique},
pages = {243--248},
publisher = {Elsevier},
volume = {333},
number = {3},
year = {2005},
doi = {10.1016/j.crme.2004.10.009},
language = {en},
}
François Jouve; Khalil Hanna. Shape optimization of an accommodative intra-ocular lens. Comptes Rendus. Mécanique, Volume 333 (2005) no. 3, pp. 243-248. doi : 10.1016/j.crme.2004.10.009. https://comptes-rendus.academie-sciences.fr/mecanique/articles/10.1016/j.crme.2004.10.009/
[1] Elastic constants of the human lens capsule, J. Physiol., Volume 201 (1969), pp. 1-19
[2] The elastic constants of the human lens, J. Physiol., Volume 212 (1971), pp. 147-180
[3] The mechanism of accommodation, Brit. J. Ophthalmol. Supplement, Volume 8 (1937), pp. 5-80
[4] Handbuch der Physiologischen Optik, Introduction to Physiological Optics, Dover, New York, 1909 (English translation, 1961)
[5] The force of contraction of the human ciliary muscle during accommodation, J. Physiol., Volume 270 (1977), pp. 51-74
[6] Measurement of accommodation after implantation of an accommodating posterior chamber intraocular lens, J. Cataract Refr. Surg., Volume 29 (2003) no. 4, pp. 677-685
[7] Clinical study of the 1CU accommodating intraocular lens, J. Cataract Refr. Surg., Volume 29 (2003) no. 7, pp. 1307-1312
[8] Shape Optimization by the Homogenization Method, Springer-Verlag, New York, 2001
[9] Shape optimization by the homogenization method, Numer. Math., Volume 76 (1997), pp. 27-68
[10] Structural optimization using sensitivity analysis and a level set method, J. Comput. Phys., Volume 194 (2004) no. 1, pp. 363-393
[11] Optimal design of micro-mechanisms by the homogenization method, Eur. J. Finite Elements, Volume 11 (2002), pp. 405-416
Cité par Sources :
Commentaires - Politique
Restored vision—augmented vision: arguments for a cybernetic vision
Jean-Louis de Bougrenet de la Tocnaye
C. R. Biol (2022)
Retinal prostheses: Clinical results and future challenges
Serge Picaud; José-Alain Sahel
C. R. Biol (2014)