Comptes Rendus
Shape optimization of an accommodative intra-ocular lens
Comptes Rendus. Mécanique, Volume 333 (2005) no. 3, pp. 243-248.

Cataract surgery consists in replacing the clouded or opacified crystalline lens by an Intra-Ocular Lens (IOL) having the same mean dioptrical power. Clear vision is then achieved at a given distance and glasses are needed in many situations. A new kind of IOL, potentially accommodative, is proposed. Its design is based on the deep understanding of the accommodation mechanism and on the mathematical modeling and the numerical simulation of the IOL's comportment in vivo. A preliminary version of this IOL is now commercialized by the company HumanOptics under the name ‘1CU’. In a second phase, shape optimization techniques equipped with strong mechanical and physiological constraints, are used to enhance the IOL performance and build a new design.

. L'opération de la cataracte consiste à remplacer le cristallin naturel devenu opaque par une lentille intraoculaire de même puissance refractive moyenne. Après une telle intervention la vision du patient est nette à une distance fixe et il doit porter des lunettes dans de nombreuses circonstances. Nous proposons un nouvel implant qui permet de préserver au moins en partie sa capacité accommodative. Sa conception repose sur la compréhension des mécanismes de l'accommodation, la modélisation et la simulation numérique du comportement de l'implant in vivo. Une version de cet implant est actuellement fabriquée et commercialisée par la société HumanOptics sous le nom de « 1CU ». Dans une seconde phase, nous décrivons comment les techniques récentes d'optimisation de forme permettent d'améliorer le design initial.

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Published online:
DOI: 10.1016/j.crme.2004.10.009
Keywords: Biomechanics, Computational solid mechanics, Shape optimization
Mot clés : Biomécanique, Mécanique des solides numérique, Optimisation de formes

François Jouve 1; Khalil Hanna 2

1 Centre de mathématiques appliquées (UMR 7641), École polytechnique, 91128 Palaiseau cedex, France
2 Hôtel Dieu Hospital, service d'ophtalmologie, 1, place du Parvis de Notre Dame, 75004 Paris, France
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François Jouve; Khalil Hanna. Shape optimization of an accommodative intra-ocular lens. Comptes Rendus. Mécanique, Volume 333 (2005) no. 3, pp. 243-248. doi : 10.1016/j.crme.2004.10.009. https://comptes-rendus.academie-sciences.fr/mecanique/articles/10.1016/j.crme.2004.10.009/

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