Outline
Comptes Rendus

A great contributor to the French urological science: Michel Daudon
Comptes Rendus. Chimie, Volume 19 (2016) no. 11-12, pp. 1389-1394.

Abstracts

The 40 years of Michel Daudon’s working life in the field of urolithiasis are difficult to sum up in a few lines. His knowledge, expertise and publications in the fields of biology, chemistry, nephrology, and eventually urology have contributed to make him a national and international recognized researcher in the understanding of the complex mechanisms of urolithogenesis. His great collaboration with the community of nephrologists, kidney physiologists, biologists, and urologists, seniors or in training, has widely contributed to improve modern and complete treatments of urolithiasis, which is at the origin of complicated urinary stones causing severe consequences on renal function and true public health problems. His hard working, his willingness, and the clarity of his presentations contributed to make him a national and international recognized lecturer in France and North Africa, where he created a network connecting laboratories with clinicians. Always looking forward in his scientific field, he has established links with approved research teams, making them interested in working on urolithiasis, even though research on urolithiasis disease seems to be less important than research on cancer.

La vie de travail de Michel Daudon ne peut se résumer en quelques lignes. Ses compétences en clinique, en biologie et en biochimie ont fait de lui un acteur reconnu sur le plan national et international dans la compréhension des mécanismes de la lithogenèse urinaire, source de calculs souvent complexes aux conséquences parfois graves. Il a largement contribué à la prise en charge moderne et complète de la lithiase urinaire, en permettant aux néphrologues cliniciens et physiologistes, aux biologistes, mais aussi aux urologues séniors et/ou en formation, de mieux cerner la complexité des calculs rénaux et leurs conséquences sur la fonction rénale ayant un impact en santé publique. Son travail incessant, sa disponibilité et la clarté de ses exposés ont contribué à le faire reconnaître comme un enseignant recherché par la communauté urologique aussi bien en France que dans les pays étrangers, notamment en Afrique du Nord, en créant des réseaux de collaboration entre laboratoires et cliniciens. Toujours en éveil scientifique, il a établi des liens avec des unités labellisées de recherche de haut niveau. Il a su les intéresser chercheurs à la lithiase urinaire, dont la genèse est au moins aussi complexe que la cancérogenèse, mais peut-être trop souvent considérée comme secondaire, bien qu’ayant des impacts de santé publique tout aussi importants, justifiant l’implication de ces structures de recherche.

Metadata
Received:
Accepted:
Published online:
DOI: 10.1016/j.crci.2014.11.004
Keywords: Urolithiasis, Urinary stone, Infrared spectrometry
Mot clés : Urolithiase, Calcul urinaire, Spectrophotométrie infrarouge

Bertrand Doré 1; Paul Meria 2

1 Académie nationale de chirurgie, Université de Poitiers, Poitiers, France
2 Académie nationale de chirurgie, service d’urologie, CHU Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris, France
@article{CRCHIM_2016__19_11-12_1389_0,
     author = {Bertrand Dor\'e and Paul Meria},
     title = {A great contributor to the {French} urological science: {Michel~Daudon}},
     journal = {Comptes Rendus. Chimie},
     pages = {1389--1394},
     publisher = {Elsevier},
     volume = {19},
     number = {11-12},
     year = {2016},
     doi = {10.1016/j.crci.2014.11.004},
     language = {en},
}
TY  - JOUR
AU  - Bertrand Doré
AU  - Paul Meria
TI  - A great contributor to the French urological science: Michel Daudon
JO  - Comptes Rendus. Chimie
PY  - 2016
SP  - 1389
EP  - 1394
VL  - 19
IS  - 11-12
PB  - Elsevier
DO  - 10.1016/j.crci.2014.11.004
LA  - en
ID  - CRCHIM_2016__19_11-12_1389_0
ER  - 
%0 Journal Article
%A Bertrand Doré
%A Paul Meria
%T A great contributor to the French urological science: Michel Daudon
%J Comptes Rendus. Chimie
%D 2016
%P 1389-1394
%V 19
%N 11-12
%I Elsevier
%R 10.1016/j.crci.2014.11.004
%G en
%F CRCHIM_2016__19_11-12_1389_0
Bertrand Doré; Paul Meria. A great contributor to the French urological science: Michel Daudon. Comptes Rendus. Chimie, Volume 19 (2016) no. 11-12, pp. 1389-1394. doi : 10.1016/j.crci.2014.11.004. https://comptes-rendus.academie-sciences.fr/chimie/articles/10.1016/j.crci.2014.11.004/

Version originale du texte intégral

1 Introduction

Almost 250 referenced publications by Michel Daudon testify to the importance of his work. A survey of his 40 working years as a biologist specialized in the field of urolithiasis appears to be truly justified. But the risk was to be reductive, since his collaborative work with his research colleagues, biologists, clinicians and physicians, was intensive.

His knowledge in the fields of biology, biochemistry and physiology applied to medicine quickly attracted specialists involved in the treatment of various diseases, characterized by crystallization phenomena, such as nephrologists, rheumatologists, cardiologists, and obviously urologists, whose main area of interest was urolithiasis.

The first publication from Michel Daudon in 1978 focused on the spectrophotometric analysis of gallbladder stones [1] and did not foresee its forthcoming intellectual “crystallization” on urinary lithogenesis and lithogenic diseases. Two meetings directed Michel Daudon’s researches on urolithiasis. The first one led him to work with R.-J. Reveillaud at the laboratory of biochemistry (CRISTAL Laboratory) in Saint-Cloud hospital, which was dedicated to urinary stone analysis. The second one allowed him to collaborate with P. Jungers, professor of nephrology at Necker hospital, in which he entered the laboratory headed by M. Lacour, after Reveillaud’s death. Such meetings initiated his passion for research and led him to seek to understand the complex mechanisms of lithogenesis, particularly those of urinary stones, and the deepest mechanisms of nephron functioning [2]. Their collaborative studies on the epidemiology of urolithiasis and the risk factors of lithogenesis contributed to the analysis and understanding of various factors increasing the risk of recurrence of urolithiasis and their clinical and economic consequences on public health [3,4].

At the beginning of the 1980s, R.J. Reveillaud and M. Daudon developed the bases of a clinical-biological confrontation between the composition and the crystalline architecture of urinary stones, most often very heterogeneous, and their association with the various and complex mechanisms involved in their formation [5].

In collaboration with P. Jungers, they studied the factors of recurrence of oxalate stones in patients treated with piridoxylate [6].

Quickly, the members of the urolithiasis committee of the French urological association (CLAFU) understood the importance of Daudon’s work in the field of stone analysis at the time when new techniques such as extracorporeal lithotripsy (ESWL), percutaneous nephrolithotomy (PCNL) and retrograde ureteroscopy were emerging.

In this article, we aim at describing this collaboration.

2 Collaborations with urologists

2.1 Clinical research

Clinical research was Daudon’s main topic.

2.1.1 The CLAFU

He was involved in clinical research right from the start of the CLAFU in 1994 and continues to help the urologists in their research themes and in the setup of recommendations and clinical guidelines [7]. The objectives of the committee remains to make the urologists sensitive to the systematic realization of efficient metabolic patient’s assessment, coupled with the physical analysis of the stones expelled after the first renal colic and that of the fragments extracted by the modern techniques of treatment. Many other themes were addressed by the committee, due to M. Daudon’s diligence and that of P. Jungers, M. Normand and J.-P. Haymann as contributing nephrologists. So, he brought his experience in various fields, such as ESWL, in which from 1989 he could foresee the importance of the frequency of the shock waves on the quality of fragmentation as well as that of the nature of the stones [8,9]. He helped the urologists to take an interest in the correlations between stone composition and lithogenic diseases [10], and between lithogenesis and different aspects of metabolism. He focused on various mechanisms related to phosphate, calcium oxalate [11], uric acid, metabolic syndrome, diabetes, pregnancy and infection [12–16].

But one of the most important contributions of M. Daudon for the urologists was to make them aware of the importance of stones collection after removal, intended for physical analysis that replaced the obsolete chemical analysis. Stone analysis with infrared spectrophotometry (SPIR) corrected many diagnostic errors previously related to the discriminative inadequacy of chemical analysis. The highlighting of the type Ic calcium oxalate monohydrated stone allowed early recognition and treatment of primary hyperoxaluria, a serious lithogenic disease affecting children and adults [17–19], in which crystalluria is a simple and reliable tool [20]. Likewise, the diffusion of the SPIR diagnosis of 2.8-dihydroxyadenin stones, related to adenine phosphoribosyl transferase deficiency, allowed many biologists taught by M. Daudon to perform an early diagnosis of such a disease [21]. Its genetic identification should facilitate preventive measures and adapted treatment (allopurinol) of this serious and recurrent disease affecting adults and children and requiring sometimes kidney transplantation [22–29].

2.1.2 Cystinuria

Daudon proposed and coordinated with the CLAFU a national survey on cystinuria. This collaborative work, assembling urologists, nephrologists and biologists, listed more than 600 patients in an exhaustive study, whose results are in press [30]. This retrospective study, focusing on a rare disease, whose treatment remains difficult, is one of the most important ones in the literature. It supplements numerous collaborative publications on clinical and fundamental research that demonstrated the pathogen mutation of a part of the Slc3a1 in an animal model, similar to the human case [31–35].

2.1.3 Endoprosthesis encrustations

The collaborative work with urologists allowed Daudon to study a diversity of encrustations in various biomaterials constituting endoprostheses, either in non-lithiasic patients with bladder indwelling catheters or in lithiasic patients with “double-J” stents after stone treatment [36]. He demonstrated that hydrogel-coated stents displayed faster encrustation than others, requiring special surveillance and frequent replacement [36–40]. Other researches were performed with cardiologists and vascular surgeons on bio-prosthesis and aortic valves [41,42].

2.1.4 Prevention of stone recurrence

Prevention of stone recurrence is a common objective of urologists and nephrologists. Daudon always focused his work on the role of the inhibitors and promoters of lithogenesis. [43].

Three peculiar aspects can be reported:

  • • drinking waters are one of the most important preventive tools against stone recurrence, by the means of the dissolution of crystals. Likewise, Daudon collaborated with urologists to evaluate the influence of different sorts of water and that of diuresis on stone recurrence [44,45]. Nevertheless, this subject remains controversial;
  • • Randall’s plaque currently displays a resurgence of interest as a cause of stone recurrence. Its role as a factor of nucleation of calcium carbonate amorphous phosphate (PACC) and calcium phosphate was addressed in numerous collaborative studies associating physicians, nephrologists and urologists under Daudon’s coordination [46–50];
  • • urolithiasis and infection have a strong and complex relation, which was widely studied by Daudon. He collaborated with physicians and urologists to assess infection stones due to urea splitting microorganisms, responsible for phosphate ammoniac magnesium (struvite) and carbapatite stones. Using spectrometry and neutronic diffraction, Daudon demonstrated that only carbapatite displayed bacterial imprints, since its crystals were smaller than those of struvite [51].

Urolithiasis in VIH-infected patients receiving antiviral agents (indinavir, ritonavir, atazanavir, darunavir, efavirenz, foscarnet) was an important theme of research for Daudon [52–54]. This work joined other researches on the relation between urolithiasis and various drugs (flumequin, amoxicillin, fluoroquinolones, oxolinic acid, piridoxilate) [55,56].

2.1.5 Correlation between CT scan and stone analysis

The results of stone treatments, particularly ESWL, are correlated with stone composition. Many works have been done by urologists and radiologists, in association with Daudon, who studied the composition of stone fragments and compared pretreatment stone density (HU) with the main component highlighted by SPIR analysis [57–59]. The comparison of stone density measurements obtained with various CT scan devices, however, did not allow the prediction of various sorts of urinary stones identified by SPIR analysis [60].

2.1.6 The French conference on urology

The collaboration between Daudon and the urologists was also materialized by an important contribution to the annual report of the French conference on urology in 2007, in which Daudon addressed various themes, such as epidemiology, lithogenesis, and its relation with the metabolic syndrome [61–63].

2.2 Teaching

Daudon contributed to spread the results of his clinical and fundamental researches toward nephrologists, biologists and urologists, with whom he continues to collaborate.

2.2.1 Teaching at the French College of Urology (enseignement du collège d’urologie [ECU])

Daudon is an active member of the different meetings organized by the French College of Urology (Collège français des urologues [CFU]), intended for young urologists in training, under the responsibility of the French Association of Urology (AFU). Likewise, he taught the trainees in the fields of lithogenesis, epidemiology, and stone classification based on SPIR analysis, correlations between stone composition and lithogenic diseases [64].

2.2.2 Workshops on urology (SUC)

Daudon was also involved in the medical continuing education intended for certified urologists. During the workshops (séminaire d’urologie continue [SUC]), he instructed them on the recent advances in stone analysis by the means of SPIR instead of chemical analysis, and contributed to a better management of urolithiasis. He focused on the absolute need for stone collection after treatment for SPIR analysis [10] and on the importance for urologists:

  • • of the knowledge of the guidelines about metabolic evaluation, recommended from the moment of the first clinical manifestation of urolithiasis, with the aim of reducing the recurrence risk [7];
  • • of the collection of stone fragments for SPIR analysis [65];
  • • of PCNL, which could be performed bilaterally and safely during the same procedure under certain conditions [66];
  • • of giving special consideration to VIH-infected patients due to the risk of upper urinary tract obstruction by drug-induced stones [67];
  • • of the removal of various sorts of stones present in the prostate during transuretral operations [68].

2.2.3 The university diploma on urolithiasis

This diploma was created 15 years ago by Daudon and remains attractive. It favors meetings between biologists, nephrologists and urologists from Europe and North Africa. All aspects of urolithiasis are covered during workshops in which numerous exchanges and brainstorming meetings are included. Young urologists are more and more frequently present and this aspect testifies to their increasing interest in lithogenesis and consequently to the exhaustive insight into urolithiasis they have got, allowing a better management of the disease, including recurrence prevention.

2.2.4 Clinical and biological confrontations on urolithiasis at Necker hospital

The increasing links between urologists, nephrologists, and biologists led to create such annual meetings 20 years ago, which were intended for a better understanding of urolithiasis and to favor exchanges on lithogenesis, preventive, and therapeutic measures. This collaborative work was extended to the radiologists and the physicians involved in fundamental research, such as D. Bazin. Consequently, young urologists could develop master research projects such as microscopic studies of stones by means of synchrotrons [69], electronic microscopic studies of Randall’s plaques and the role of heavy elements such as zinc and strontium in calcic lithogenesis and selenium in cystine lithogenesis [70].

2.2.5 Contribution to educational materials in urology

Daudon contributed to many textbooks and articles dedicated to urolithiasis. He aimed to help all physicians, including nephrologists and urologists certified or in training, to improve their knowledge in the field of urolithiasis and understand the complex lithogenic mechanisms so that they could:

  • • adapt their handling of urolithiasis, which is a public health problem;
  • • reduce the recurrence risk, which can be cost-effective for the healthcare system [71].

Two editions of collaborative books were published, associating nephrologists with biologists and urologists. They presented an exhaustive and updated survey on urolithiasis, including the recent advances, as an expression of Daudon’s willingness in the transmission of validated knowledge [72,73].

3 Conclusions

The importance of Daudon’s work in the field of urolithiasis is a trump card for the community of urologists who were lucky to meet him. His contribution to a better understanding of lithogenesis, his emphasis on systematic physical analysis of stone fragments after urologic treatment may hopefully point to a reduction of the stone recurrence rate, which remains at a high level although technical progress.

The future must be imagined. Daudon is an unresting worker and the urologists hope they will rely on his successor, whose task will be hard.

Indeed, urolithiasis, the core of our job, found in M. Daudon its cornerstone: his original work must resist to the shock waves of the passage of time…


References

[1] M. Daudon; M.-F. Protat; R.-J. Reveillaud Analysis of gallstones by infrared spectrophotometry. Advantages and limits of the method, Ann. Biol. Clin. (Paris), Volume 36 (1978), pp. 475-489

[2] R.-J. Reveillaud; G. Blanc; M. Daudon Nephrotic syndrome and skin disorders appearing during alpha-mercapto-propionyl-glycine treatment of 2 cases of cystinic lithiasis, J. Urol. Nephrol. (Paris), Volume 84 (1978), pp. 663-667

[3] R.-J. Reveillaud; M. Daudon Recurrent oxalo-calcium lithiasis. Epidemiology, composition and theories of calculi formation: crystallization factors, Rev. Prat., Volume 39 (1989), pp. 141-148

[4] R.-J. Réveillaud; M. Daudon Recurrent oxalocalcium lithiasis. Risk factors and prevention of recurrence of calcium urinary lithiasis, Rev. Prat., Volume 39 (1989), pp. 317-323

[5] R.-J. Reveillaud; M. Daudon; M.-F. Protat; G. Ayrole Analysis of urinary calculi in adults. Attempt of correlations between morphology and composition, Eur. Urol., Volume 6 (1980), pp. 161-165

[6] M. Daudon; R.-J. Reveillaud; P. Jungers Recurrent calcium oxalate calculi in patients treated with piridoxylate, Presse Med., Volume 14 (1985), pp. 846-847

[7] J.-P. Haymann; M. Daudon; M. Normand; A. Hoznek; P. Meria; Traxer et les membres du CLAFU First-line screening guidelines for renal stone disease patients: a CLAFU update, Prog. Urol., Volume 24 (2014), pp. 9-12

[8] G. Vallancien; R. Munoz; M. Borghi; B. Veillon; J.M. Brisset; M. Daudon Relationship between the frequency of piezoelectric shock waves and the quality of renal stone fragmentation. In vitro study and clinical implications, Eur. Urol., Volume 16 (1989), pp. 41-44

[9] P. Léger; M. Daudon; M. Magnier In vitro test of piezoelectric lithotripsy with ultrasound detection using an EDAP LT 01 lithotripser, J. Urol., Volume 96 (1990), pp. 353-364

[10] M. Daudon; C.A. Bader; P. Jungers Urinary calculi: review of classification methods and correlations with etiology, Scanning Microsc., Volume 7 (1993), pp. 1081-1104 (discussion 1104–6)

[11] M. Daudon; R.-J. Réveillaud Whewellite and weddellite: toward a different etiopathogenesis. The significance of morphological typing of calculi, Nephrologie, Volume 5 (1984), pp. 195-201

[12] O. Traxer; H. Safar; M. Daudon; J.-P. Haymann Metabolic syndrome, obesity and urolithiasis, Prog. Urol., Volume 16 (2006), pp. 418-420

[13] M. Daudon; P. Jungers Diabetes and nephrolithiasis, Curr. Diab. Rep., Volume 7 (2007), pp. 443-448

[14] M. Daudon; O. Traxer; P. Conort; B. Lacour; P. Jungers Type 2 diabetes increases the risk for uric acid stones, J. Am. Soc. Nephrol., Volume 17 (2006), pp. 2026-2033

[15] M. Daudon; B. Lacour; P. Jungers High prevalence of uric acid calculi in diabetic stone formers, Nephrol. Dial. Transplant., Volume 20 (2005), pp. 468-469

[16] P. Méria; H. Hadjadj; P. Jungers; M. Daudon; Members of the French Urological Association Urolithiasis Committee Stone formation and pregnancy: pathophysiological insights gained from morphoconstitutional stone analysis, J. Urol., Volume 183 (2010), pp. 1412-1416

[17] M. Daudon; P. Jungers; D. Bazin Stones in primary hyperoxaluria – a clarification, N. Engl. J. Med., Volume 359 (2008), pp. 100-102

[18] M. Daudon; P. Jungers; D. Bazin Peculiar morphology of stones in primary hyperoxaluria, N. Engl. J. Med., Volume 359 (2008), pp. 100-102 (Comment in N. Engl. J. Med. 360 (2009) 1680)

[19] P. Cochat; S.A. Hulton; C. Acquaviva; C.J. Danpure; M. Daudon; M. De Marchi; S. Fargue; J. Groothoff; J. Harambat; B. Hoppe; N.V. Jamieson; M.J. Kemper; G. Mandrile; M. Marangella; S. Picca; G. Rumsby; E. Salido; M. Straub; C.S. van Woerden; OxalEurope Primary hyperoxaluria type 1: indications for screening and guidance for diagnosis and treatment, Nephrol. Dial. Transplant., Volume 27 (2012), pp. 1729-1736

[20] P. Jouvet; L. Priqueler; M.-F. Gagnadoux; D. Jan; A. Beringer; F. Lacaille; Y. Revillon; M. Broyer; M. Daudon Crystalluria: a clinically useful investigation in children with primary hyperoxaluria post-transplantation, Kidney Int., Volume 53 (1998), pp. 1412-1416

[21] R.-J. Reveillaud; M. Daudon; M.-F. Protat; A. Vincens; D. Graveleau Lithiase de 2, 8-dihydroxyadenine : un nouveau cas détecté par analyse infrarouge, Nouv. Presse Med., Volume 8 (1979) no. 37, pp. 2965-2966

[22] I. Ceballos-Picot; M. Daudon; J. Harambat; A. Bensman; B. Knebelmann; G. Bollée 2, 8-dihydroxyadenine urolithiasis: a not so rare inborn error of purine metabolism, Nucleosides Nucleotides Nucleic Acids, Volume 33 (2014) no. 4–6, pp. 241-252

[23] G. Bollée; C. Dollinger; L. Boutaud; D. Guillemot; A. Bensman; J. Harambat; P. Deteix; M. Daudon; B. Knebelmann; I. Ceballos-Picot Phenotype and genotype characterization of adenine phosphoribosyltransferase deficiency, J. Am. Soc. Nephrol., Volume 21 (2010), pp. 679-688

[24] I. Ceballos-Picot; G. Guest; V. Moriniere; L. Mockel; M. Daudon; V. Malan; C. Antignac; L. Heidet Maternal uniparental disomy of chromosome 16 in a patient with adenine phosphoribosyltransferase deficiency, Clin. Genet., Volume 80 (2011), pp. 199-201

[25] E.R. Gagné; E. Deland; M. Daudon; L.H. Noël; T. Nawar Chronic renal failure secondary to 2, 8-dihydroxyadenine deposition: the first report of recurrence in a kidney transplant, Am. J. Kidney Dis., Volume 24 (1994), pp. 104-107

[26] P. Stratta; G.B. Fogazzi; C. Canavese; A. Airoldi; R. Fenoglio; C. Bozzola; I. Ceballos-Picot; G. Bollée; M. Daudon Decreased kidney function and crystal deposition in the tubules after kidney transplant, Am. J. Kidney Dis., Volume 56 (2010), pp. 585-590

[27] G. Bollée; J. Harambat; A. Bensman; B. Knebelmann; M. Daudon; I. Ceballos-Picot Adenine phosphoribosyltransferase deficiency, Clin. J. Am. Soc. Nephrol., Volume 7 (2012), pp. 1521-1527

[28] M. Hoffmann; A. Talaszka; J.-P. Bocquet; H. Le Monies de Sagazan; M. Daudon Acute renal failure and 2, 8-dihydroxyadeninuria, Nephrologie, Volume 25 (2004), pp. 297-300

[29] J. Harambat; G. Bollée; M. Daudon; I. Ceballos-Picot; A. Bensman; APRT Study Group collaborators; T. Boussemart; G. Champion; S. Taque; M. Almeida; D. Bernon; C. Dheu; S.F. Monleón; B. Horen; A. Garnier; G. Guest; A. Godron; B. Knebelmann; B. Llanas; G. Marra; M. Rincé; J.-F. Subra; F. Vrtovsnik Adenine phosphoribosyltransferase deficiency in children, Pediatr. Nephrol., Volume 27 (2012), pp. 571-579

[30] C. Prot-Bertoye; S. Lebbah; M. Daudon; M. Courbebaisse Chronic kidney disease and its determinants among cystinuric patients, J. Am. Soc. Nephrol. (2014) (soumis)

[31] M. Livrozet; S. Vandermeersch; L. Mesnard; E. Thioulouse; J. Jaubert; J.-J. Boffa; J.-P. Haymann; L. Baud; D. Bazin; M. Daudon; E. Letavernier An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice, PLoS One, Volume 9 (2014), p. e102700 (eCollection 2014) | DOI

[32] H. Bouzidi; M. Daudon Cystinurie : du diagnostic au suivi, Ann. Biol. Clin., Volume 65 (2007), pp. 473-481

[33] M. Daudon; F. Cohen-Solal; F. Barbey; M.-F. Gagnadoux; B. Knebelmann; P. Jungers Cystine crystal volume determination: a useful tool in the management of cystinuric patients, Urol. Res., Volume 31 (2003), pp. 207-211

[34] P. Jungers; D. Joly; M.-F. Gagnadoux; M. Daudon Lithiase cystinique : physiopathologie et traitement médical, Prog. Urol., Volume 11 (2001), pp. 122-126

[35] F. Barbey; D. Joly; P. Rieu; A. Méjean; M. Daudon; P. Jungers Medical treatment of cystinuria: critical reappraisal of long-term results, J. Urol., Volume 163 (2000), pp. 1419-1423

[36] H. Bouzidi; O. Traxer; B. Doré; J. Amiel; H. Hadjadj; P. Conort; M. Daudon Characteristics of encrustation of ureteric stents in patients with urinary stones, Prog. Urol., Volume 18 (2008), pp. 230-237

[37] O. Traxer; M. Anidjar; F. Gaudez; F. Saporta; M. Daudon; A. Cortesse; F. Desgrandchamps; O. Cussenot; P. Teillac; A. Le Duc A new prostatic stent for the treatment of benign prostatic hyperplasia in high-risk patients, Eur. Urol., Volume 38 (2000), pp. 272-278

[38] F. Desgrandchamps; F. Moulinier; M. Daudon; P. Teillac; A. Le Duc An in vitro comparison of urease-induced encrustation of JJ stents in human urine, Br. J. Urol., Volume 79 (1997), pp. 24-27

[39] M. Roupret; V. Hupertan; M. Daudon; S. Lebrun; P. Sebe; B. Gattegno; P. Thibault; O. Traxer Value of infrared spectrophotometry morpho-constitutional analysis of double J stent encrustations for indirect determination of urinary stone composition, Prog. Urol., Volume 15 (2005), pp. 411-415

[40] M. Rouprêt; M. Daudon; V. Hupertan; B. Gattegno; P. Thibault; O. Traxer Can ureteral stent encrustation analysis predict urinary stone composition?, Urology, Volume 66 (2005), pp. 246-251

[41] M. Shen; A. Kara-Mostefa; L. Chen; M. Daudon; M. Thevenin; B. Lacour Carpentier effect of ethanol and ether in the prevention of calcification of bioprostheses, Ann. Thorac. Surg., Volume 71 (2001) no. 5 Suppl., p. S413-S416

[42] M. Shen; P.S. Lajos; D. Farge; M. Daudon; S.M. Carpentier; L. Chen; B. Martinet; A.F. Carpentier Infrared spectroscopy in the evaluation of the process of calcification of valvular bioprostheses, Ann. Thorac. Surg., Volume 66 (1998) no. 6 Suppl., p. S236-S239

[43] B. Dussol; S. Geider; A. Lilova; F. Léonetti; P. Dupuy; M. Daudon; Y. Berland; J.-C. Dagorn; J.-M. Verdier Analysis of the soluble organic matrix of five morphologically different kidney stones. Evidence for a specific role of albumin in the constitution of the stone protein matrix, Urol. Res., Volume 23 (1995), pp. 45-51

[44] J. Hubert; C. Hubert; P. Jungers; M. Daudon; P. Hartemann Drinking water and urinary stones. Which drinking water and which modalities of diuresis?, Prog. Urol., Volume 12 (2002), pp. 692-699

[45] Y. Lotan; I. Buendia Jiménez; I. Lenoir-Wijnkoop; M. Daudon; L. Molinier; I. Tack; M.J. Nuijten Increased water intake as a prevention strategy for recurrent urolithiasis: major impact of compliance on cost-effectiveness, J. Urol., Volume 189 (2013), pp. 935-939

[46] M. Daudon; D. Bazin; E. Letavernier Randall’s plaque as the origin of calcium oxalate kidney stones, Urolithiasis (2014) (Epub ahead of print), Springer Link

[47] M. Daudon; D. Vitamin Randall plaques and nephrolithiasis: are they related?, Arch. Pediatr., Volume 20 (2013), pp. 336-340

[48] K. Bouchireb; O. Boyer; C. Pietrement; H. Nivet; H. Martelli; O. Dunand; F. Nobili; G.L. Sylvie; P. Niaudet; R. Salomon; M. Daudon Papillary stones with Randall’s plaques in children: clinicobiological features and outcome, Nephrol. Dial. Transplant., Volume 27 (2012), pp. 1529-1534

[49] X. Carpentier; D. Bazin; C. Combes; A. Mazouyes; S. Rouzière; P.A. Albouy; E. Foy; M. Daudon High Zn content of Randall’s plaque: a μ-X-ray fluorescence investigation, J. Trace Elem. Med. Biol., Volume 25 (2011), pp. 160-165

[50] X. Carpentier; D. Bazin; P. Jungers; S. Reguer; D. Thiaudière; M. Daudon The pathogenesis of Randall’s plaque: a papilla cartography of Ca compounds through an ex vivo investigation based on XANES spectroscopy, J. Synchrotron Radiat., Volume 17 (2010), pp. 374-379

[51] D. Bazin; G. André; R. Weil; G. Matzen; V. Emmanuel; X. Carpentier; M. Daudon Absence of bacterial imprints on struvite-containing kidney stones: a structural investigation at the mesoscopic and atomic scale, Urology, Volume 79 (2012), pp. 786-790

[52] V. de Lastours; E. Ferrari Rafael De Silva; M. Daudon; R. Porcher; B. Loze; H. Sauvageon; J.-M. Molina High levels of atazanavir and darunavir in urine and crystalluria in asymptomatic patients, J. Antimicrob. Chemother., Volume 68 (2013), pp. 1850-1856

[53] D. Viglietti; J. Verine; N. De Castro; A. Scemla; M. Daudon; D. Glotz; E. Pillebout Chronic interstitial nephritis in an HIV type-1-infected patient receiving ritonavir-boosted atazanavir, Antivir. Ther., Volume 16 (2011), pp. 119-121

[54] C. Couzigou; M. Daudon; J.-L. Meynard; F. Borsa-Lebas; D. Higueret; L. Escaut; D. Zucman; J.-Y. Liotier; J.-L. Quencez; K. Asselah; T. May; D. Neau; D. Vittecoq Urolithiasis in HIV-positive patients treated with atazanavir, Clin. Infect. Dis., Volume 45 (2007), pp. 105-108

[55] A. Servais; M. Daudon; B. Knebelman Drug-induced renal calculi, Ann. Urol. (Paris), Volume 40 (2006), pp. 57-68

[56] G.B. Fogazzi; M. Cantù; L. Saglimbeni; M. Daudon Amoxycillin, a rare but possible cause of crystalluria, Nephrol. Dial. Transplant., Volume 18 (2003), pp. 212-214

[57] M.-F. Bellin; R. Renard-Penna; P. Conort; A. Bissery; J.-B. Méric; M. Daudon; A. Mallet; F. Richard; P. Grenier Helical CT evaluation of the chemical composition of urinary tract calculi with a discriminant analysis of CT-attenuation values and density, Eur. Radiol., Volume 14 (2004), pp. 2134-2140

[58] R. Grosjean; B. Sauer; R.M. Guerra; M. Daudon; A. Blum; J. Felblinger; J. Hubert Characterization of human renal stones with MDCT: advantage of dual energy and limitations due to respiratory motion, AJR Am. J. Roentgenol., Volume 190 (2008), pp. 720-728

[59] G. Chevreau; J. Troccaz; P. Conort; R. Renard-Penna; A. Mallet; M. Daudon; P. Mozer Estimation of urinary stone composition by automated processing of CT images, Urol. Res., Volume 37 (2009), pp. 241-245

[60] R. Grosjean; M. Daudon; M.-F. Chammas; M. Claudon; P. Eschwege; J. Felblinger; J. Hubert Pitfalls in urinary stone identification using CT attenuation values: are we getting the same information on different scanner models?, Eur. J. Radiol., Volume 82 (2013), pp. 1201-1206

[61] M. Daudon; O. Traxer; É. Lechevallier; C. Saussine Epidemiology of urolithiasis, Prog. Urol., Volume 18 (2008), pp. 802-814

[62] M. Daudon; O. Traxer; É. Lechevallier; C. Saussine Lithogenesis, Prog. Urol., Volume 18 (2008), pp. 815-827

[63] O. Traxer; É. Lechevallier; C. Saussine; M. Daudon; J.-P. Haymann Metabolic syndrome and urolithiasis. A new concept for the urologist, Prog. Urol., Volume 18 (2008), p. 8 (28–31)

[64] X. Carpentier; M. Daudon; O. Traxer; P. Jungers; A. Mazouyes; G. Matzen; E. Véron; D. Bazin Relationships between carbonation rate of carbapatite and morphologic characteristics of calcium phosphate stones and etiology, Urology, Volume 73 (2009), pp. 968-975

[65] M. Daudon; H.V. Nguyen; R.-J. Réveillaud; P. Teillac; M. Lombard; A. Joerg; A. Cortesse; A. Le Duc Should fragments of stone expelled after extracorporeal lithotripsy always be analyzed?, Presse Med., Volume 19 (1990), pp. 251-254

[66] P. Conort; O.R. Bah; I. Tostivint; V. Cardot; H. Hadjadj; M. Daudon; M.O. Bitker; P. Mozer Simultaneous bilateral percutaneous nephrolithotomy: series of 60 cases, Prog. Urol., Volume 20 (2010), pp. 1194-1199

[67] H. Izzedine; M.B. M’rad; A. Bardier; M. Daudon; D. Salmon Atazanavir crystal nephropathy, AIDS, Volume 21 (2007), pp. 2357-2358

[68] A. Dessombz; P. Méria; D. Bazin; E. Foy; S. Rouzière; R. Weil; M. Daudon Revisiting the chemical diversity in prostatic calculi: a SEM and FT-IR investigation, Prog. Urol., Volume 21 (2011), pp. 940-945

[69] D. Bazin; X. Carpentier; O. Traxer; D. Thiaudière; A. Somogyi; S. Reguer; G. Waychunas; P. Jungers; M. Daudon Very first tests on SOLEIL regarding the Zn environment in pathological calcifications made of apatite determined by X-ray absorption spectroscopy, J. Synchrotron Radiat., Volume 15 (2008) no. Pt 5, pp. 506-509

[70] D. Bazin; P. Chevallier; G. Matzen; P. Jungers; M. Daudon Heavy elements in urinary stones, Urol. Res., Volume 35 (2007), pp. 179-184

[71] M. Daudon; B. Doré Cristallographie des calculs urinaires. Aspects néphrologiques et urologiques, EMC 18-104-A-25, Elsevier SAS, Paris, 1999

[72] P. Jungers; M. Daudon; P. Conort Lithiase rénale. Diagnostic et traitement, Médecine Sciences, Flammarion, Paris, 1999

[73] P. Jungers; O. Traxer; M. Daudon La lithiase urinaire, Médecine Sciences Publications, Lavoisier, Paris, 2012


Comments - Policy